5 Favorites for Biotech Stock Buyers

Market volatility has risen sharply as investors react to short-term geopolitical news. In the biotech sector, however, investment experts tend to remain focused on long-term developments such as clinical drug trials. For those with a long-term horizon, here are some favorites from MoneyShow.com contributors.

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MTSL Issue 892

MTSL Issue 892 (dated 12/13/18) of the Medical Technology Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #IONS #MDGL #MDCO

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MTSL Issue 876

MTSL Issue 876 (dated 04/26/18) of Medical Technology Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ACAD #ALKS #BMRN #IONS #INCY #MDCO #NKTR

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MTSL Issue 874

MTSL Issue 874 (dated 03/29/18) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ESPR #FPRX #IONS #XON #MDGL

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Nektar

Nektar (NKTR) Continues Charge Forward With ‘181 & ‘214 Leading The Way

BioInvest News – Nektar (NKTR) Continues Charge Forward With ‘181 & ‘214 Leading The Way. On the recent Q4 conference call, NKTR provided updates for both ‘181 and ‘214. The company has had two positive pre-NDA meetings with the FDA over the last two months regarding ‘181. One very important aspect discussed with the agency is a better abuse scheduling for ‘181 given its non-addictive properties than a Schedule 2 which is currently used for addictive opioids.

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Nektar

Nektar (NKTR) Inks The Ultimate Monster Deal With BMS For NKTR-214

BioInvest News – Nektar (NKTR) NKTR has signed the largest single product deal in biotech history with BMS for their leading I/O development candidate NKTR-214. Clearly BMS paid handsomely for what may have been the most attractive asset in the space.

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MoneyShow’s Top Stock Pickers of 2017

Biotechnology expert John McCamant deserves special recognition; his top pick from last year rose an astounding 519%. We’ve asked John, and all these other outstanding advisors, to share their updated opinions on these top performing stocks from last year’s Top Picks 2017 report.

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MTSL Issue 865

MTSL Issue 865 (dated 11/23/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #FPRX #XON #NKTR #PCRX #SGMO #ZIOP

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MTSL Issue 861

MTSL Issue 861 (dated 9/28/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ALKS #MDGL #NKTR

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MTSL Issue 857

MTSL Issue 857 (dated 7/27/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ALKS #ESPR #INCY #IONS #MDCO #NKTR #NVAX #PCRX

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MTSL Issue 853

MTSL Issue 853 (dated 6/01/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #BMRN #IONS #NKTR

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Complimentary MTSL Issue

Complimentary Issue (dated 5/04/17) of Medical Technology Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: ALKS BMRN CELG ESPR FPRX INCY IONS MDCO PCRX SGMO ZIOP

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Medicines Company

The Medicines Company (MDCO) Inclisiran FDA Path Clear After End of Phase II Meeting – Lower Risk, Value Enhanced

BIOINVEST BREAKING NEWS – The Medicines Company (MDCO) – Inclisiran FDA Path Clear After End of Phase II Meeting – Lower Risk, Value Enhanced – The Medicines Company announced that the primary endpoint of the Phase III registrational trial will be LDL-C levels. This is a major positive for MDCO – significantly reduces the risk and increases the value of Inclisiran.

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MTSL Issue 849

MTSL Issue 849 (dated 3/30/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ALKS #ANTH #ESPR #IONS #NKTR #SGMO #ZIOP

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MTSL Issue 848

MTSL Issue 848 (dated 3/16/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ANTH #ESPR #IONS #XON #MDCO #OGXI #PCRX

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MTSL Issue 846

MTSL Issue 846 (dated 2/16/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ALKS #ESPR (new) #INCY #IONS

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MTSL Issue 843

MTSL Issue 843 (dated 1/5/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ACAD #ANTH #INCY #IONS #MDCO

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MTSL Issue 841

MTSL Issue 841 (dated 12/1/16) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ACAD #MDGL #SGMO

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MTSL Issue 840

MTSL Issue 840 (dated 11/17/16) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ANTH #IONS #MDCO #NVAX #ZIOP

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Trump Victory Brings V-Shaped Reaction (11-9-16)

The immediate reaction of a widely unexpected Republican sweep was a huge across the board rally in health care stocks. While it is still very early make definitive conclusions, several positive impacts have resulted in a major reversal of sentiment. Today’s impressive rally (NBI +8%) is a likelihood of some combination of the following macro fundamental and technical changes that are expected to occur with a new, right leaning administration.

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MTSL Issue 837

MTSL Issue 837 (10/06/16) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ACAD #INCY #IONS #MDCO #NKTR #XON

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‘Access to Management’ Conference Call with Anthera (ANTH) 9-1-16

BIOINVEST Access to Management Webinar – Anthera (ANTH)– We are pleased to announce another BioInvest “Access to Management Call.” Below is the link to the recorded webinar presentation with the Senior Management Team of Anthera.

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MTSL Issue 833

MTSL Issue 833 (dated 8/11/16) of Medical Technology #Stock Letter from BioInvest includes the #Biotech Sector Analysis & updates from these companies: #ACAD #ANTH #BMRN #FPRX #INCY #XON #IONS #MDCO #NKTR #NVAX #PCRX #SGMO #ZIOP

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Ziopharm

Special Update – Ziopharm (ZIOP) – 3 Patients Die In The IL-12 Trial

BIOINVEST BREAKING NEWS – Special Update – Ziopharm (ZIOP) – 3 Patients Die In The IL-12 Trial. ZIOP is down sharply this morning (7/15) on the report that three patients have died in their ongoing multicenter Phase I trial of Ad-RTS-hIL-12 + orally administered veledimex in recurrent or progressive glioblastoma (GBM) or grade III malignant glioma.

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‘Access to Management’ Conference Call with Novavax (NVAX) 6-3-16

BIOINVEST Access to Management Webinar – Novavax (NVAX)– We are pleased to announce another BioInvest “Access to Management Call.” Below is the link to the recorded webinar presentation with the Senior Management Team of Novavax.

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Acadia

Acadia (ACAD) — In Perfect HARMONY

BIOINVEST BREAKING NEWS – Special Update – ACAD — In Perfect HARMONY–This morning, ACAD released excellent data from the Phase III HARMONY study, a double-blind, placebo-controlled relapse prevention trial evaluating pimavanserin for the treatment of dementia-related psychosis.  Read more…

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Sangamo Therapeutics

Sangamo (SGMO) – Q2 CALL BONANZA – Reiterate BUY (And Short CRSP, EDIT, NTLA)

BioInvest BREAKING News – SANGAMO – Q2 CALL BONANZA – Reiterate BUY (And Short CRSP, EDIT, NTLA) First Hemophilia A SB-525 Results Ideal In The ALTA Study-MPSII Patient 6 Treated with SB-913 in the CHAMPIONS Study
-First patient treated in the SB-318 Phase 1/2 EMPOWERS Study for MPS Enrolled the first patient in the Phase 1/2 Thales Study of ST-400 gene-edited cell therapy for beta-thalassemia
Presented further ZFN Safety via the Most Sensitive Assays ..

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MTSL Issue 875

MTSL Issue 875 (dated 04/12/18) of Medical Technology Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ACAD #ALKS #INCY #IONS #NKTR #PCRX

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MTSL Issue 873

MTSL Issue 873 (dated 03/15/18) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ANTH #ESPR #IONS #MDGL #ZIOP

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Sangamo Therapeutics

Sangamo (SGMO) Powerful Deal With GILD/KITE For ZFNs In Next Generation Off-The-Shelf CAR-Ts

BioInvest News – SGMO – Powerful Deal With GILD/KITE For ZFNs In Next Generation Off-The-Shelf CAR-Ts – Raising BUY to 30 & TARGET PRICE TO 40 – Despite being pre-clinical and early stage, GILD is paying $150 million upfront in cash and up to $3.1 billion in milestones plus tiered royalties on 10 SGMO-derived cancer drug candidates (or $300 million per product). Combining the KITE/GIlD expertise and infrastructure – with SGMO – will create a transformative leader in the field.

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Madrigal

Madrigal (MDGL) MGL-3196 Delivers Positive Phase II HeFH Data

BioInvest News – Madrigal (MDGL) – MGL-3196 Delivers Positive Phase II HeFH Data – MDGL has released positive top-line HeFH Phase II data. The trial enrolled 116 patients who were not at their LDL-C goal and were randomized in a 2:1 ratio to receive either MGL-3196 or placebo, in addition to their current cholesterol lowering regimen, which included approximately 75% taking high intensity statins (20/40 mg rosuvastatin or 80 mg atorvastatin), and about 2/3 of patients also taking ezetimibe.

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MTSL Issue 869

MTSL Issue 869 (dated 01/18/18) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ALKS #ESPR #INCY #MDGL #MDCO #NKTR #PCRX #SGMO #ZIOP

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MTSL Issue 867

UPDATES: BMRN, INCY, IONS, MDGL, NKTR, NVAX, SGMO, December 21, 2017 IN THIS ISSUE: MDGL, NKTR & SGMO: The Three Amigos Will Rise Again in 2018 Since Last Issue: BTK: 0.0%; NBI: 2.6%; Model Portfolio: 2.6%; Trader’s Portfolio: 2.4% Clinical Trials Watch Relevant New Studies or Changes Posted on ClinicalTrials.gov for our MTSL Portfolio and/or[…]

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MTSL Issue 863

MTSL Issue 863 (dated 10/26/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ALKS #ESPR #INCY #XON #MDGL #MDCO

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MTSL Issue 860

MTSL Issue 860 (dated 9/14/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #FPRX #INCY #IONS #NKTR #SGMO

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MTSL Issue 859

MTSL Issue 859 (dated 8/31/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ANTH #BMRN #FPRX #INCY #IONS #DCO NKTR #NVAX SGMO

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Novavax

Novavax (NVAX) Delivers Some Positive Phase II Immunogenicity Data In COPD

BioInvest News – NVAX – Delivers Some Positive Phase II Immunogenicity Data In COPD…Investors Wanted an RSV Update – NVAX reported top line data from the Phase II older adult safety and immunogenicity trial (E205) demonstrated the benefit of adjuvant formulations and two-dose regimens in patients with RSV and chronic obstructive pulmonary disease (COPD).

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MTSL Issue 855

MTSL Issue 855 (dated 6/29/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ALKS #ESPR #SGMO #ZIOP

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MTSL Issue 852

MTSL Issue 852 (dated 5/18/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #INCY #XON #IONS #NKTR #NVAX #SGMO #ZIOP

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Sangamo Therapeutics

Sangamo (SGMO) PFE Global Deal for Hemophilia A Has Many Positive Implications

Breaking News – Sangamo Therapeutics (SGMO) – PFE Global Deal for Hemophilia A Has Many Positive Implications – In a very competitive bidding process SGMO has inked a significant global partnership with Pfizer, who brings a wealth of value to SGMO, and notably validates the latter company’s gene therapy platform.

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MTSL Issue 850

MTSL Issue 850 (dated 4/20/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #IONS #INCY #MDGL #NKTR #ZIOP

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Esperion

Esperion Therapeutics (ESPR) – FDA Shows Esperion “The Way to Approval”

BIOINVEST BREAKING NEWS – Esperion Therapeutics (ESPR) – FDA Shows Esperion “The Way to Approval” – Raising BUY to 40 and TARGET PRICE to 60

This morning, ESPR announced that the FDA has confirmed that the bempedoic acid Phase III development program is adequate to support an approval prior to their CVOT results, lifting one of the largest overhangs on the stock, and creating a clear path to an earlier-than-expected approval.

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MTSL Issue 847

MTSL Issue 847 (dated 3/02/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ACAD #BMRN #CELG #FPRX #INCY #XON #IONS #MDCO #NKTR #PCRX #SGMO

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MTSL Issue 845

MTSL Issue 845 (dated 2/02/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #INCY #XON #MDCO #NVAX #PCRX

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MTSL Issue 844

MTSL Issue 844 (dated 1/19/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ACAD #BMRN #CELG #INCY #IONS #MDCO #NKTR #PCRX #SGMO #ZIOP

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Medicines Company

The Medicines Company (MDCO) Discontinues ‘216 – AHA Meeting Next Week

BIOINVEST Update – The Medicines Company (MDCO) – – Discontinues ‘216 – AHA Meeting Next Week

News – MDCO Stops MDCO-216 After Pilot Trial Unsuccessful – The pilot trial did not show efficacy – there was no positive effect on atherosclerosis. Safety was fine. The data calls into question the viability of APO-A1 Milano as a target and the positive implications of HDL as well.

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Madrigal

New Recommendation – Madrigal Pharmaceuticals (MDGL) – Paul Friedman Is Back

BIOINVEST Update – (New Recommendation) Madrigal Pharmaceuticals (MDGL) – Paul Friedman Is Back

NASH is a hot topic in Biotech since September when Allergan bought Tobira Therapeutics (TBRA) for a stunning $1.7 billion for a Phase II asset. The Tobira deal was done at a tremendous 500% premium and topped the $1.2 billion Gilead paid for a NASH drug candidate being developed by Nimbus Therapeutics.

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MTSL Issue 836

MTSL Issue 836 (dated 9/22/16) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #IONS #MDCO #NVAX #PCRX

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MTSL Issue 834

MTSL Issue 834 (dated 8/25/16) of Medical Technology #Stock Letter from BioInvest includes the #Biotech Sector Analysis & updates from these companies: #ANTH and #OGXI

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MTSL Issue 832

MTSL Issue 832 (dated 7/28/16) of Medical Technology #Stock Letter from BioInvest includes the #Biotech Sector Analysis & updates from these companies: #ALKS #BMRN #INCY #MDCO #SGMO

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MTSL Issue 830

MTSL Issue 830 (dated 6/30/16) of the Medical Technology #Stock Letter from BioInvest includes the #Biotech Sector Analysis as well as updates from the following companies: #ANTH #BMRN #FPRX #INCY #IONS #MDCO #ZIOP

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MTSL Issue 828

MTSL Issue 828 (dated 5/26/16) of the Medical Technology #Stock Letter from BioInvest includes the #Biotech Sector Analysis as well as updates from the following companies: #

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Medicines Company

The Medicines Company (MDCO) — Inclisiran Indeed! 

The Medicines Company (MDCO) – Inclisiran Indeed!  Following up on the positive top-line results of the ORION 11 trial (released 8/26), the actual data presented at the ESC Congress 2019 were uniformly favorable for both efficacy and safety. In addition, despite the relatively smaller study and not powered for outcomes (n=1607), there was a strong reduction in Cardio Vascular Outcomes (CVO) in the Inclisiran treated arm versus placebo. (… more)

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MTSL Issue 893

MTSL Issue 893 (dated 1/3/18) of the Medical Technology Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #INCY #NVAX #PCRX #ZIOP

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Biotech Investors Should Consider The Four Horsemen

CRISPR Chaos: 3 Shorts And A Buy In Gene Editing

In a rare move for a biotech expert who primarily takes bullish long-term positions, John McCamant has issued short sale recommendations for three stocks in the CRISPR space. The editor of The Medical Technology Stock Letter and contributor to MoneyShow.com explains his concerns about this specialized group while also reiterating a Strong Buy rating for one gene-editing play which does not rely on CRISPR technology.

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Biotech Investors Should Consider The Four Horsemen

Biotech Investors Should Consider The Four Horsemen

One of the keys to long-term biotech investing is finding the big winners and riding them to huge gains, writes Medical Technology Stock Letter editor John McCamant and frequent MoneyShow.com contributor. Medical Technology Stock Letter has had many such winners over the years, including Genentech and Pharmacyclics. We provided multiple entry points to invest in Pharmacyclics starting at $17 and in three-plus years the company was sold to AbbVie for $262 per share or $21 billion. Over the last year and a quarter, our subscribers have been enjoying incredible gains with the Four Horsemen: Esperion Therapeutics. Madrigal Pharmaceuticals, Nektar Therapeutics, Sangamo Therapeutics.

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MTSL Issue 872

MTSL Issue 872 (dated 03/01/18) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ACAD #FPRX #IONS #MDCO #NKTR #NVAX #PCRX #SGMO

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MTSL Issue 871

MTSL Issue 871 (dated 02/15/18) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ALKS #INCY #IONS #MDGL #NKTR #PCRX #SGMO #ZIOP

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MTSL Issue 870

MTSL Issue 870 (dated 02/01/18) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ALKS #FPRX #MDGL #MDCO #NKTR

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MTSL Issue 868

MTSL Issue 868 (dated 01/04/18) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ESPR #FPRX #PCRX #SGMO

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MTSL Issue 866

MTSL Issue 866 (dated 12/07/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ALKS #MDGL #MDCO #NVAX

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MTSL Issue 864

MTSL Issue 864 (dated 11/09/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ACAD #ESPR #FPRX #INCY #IONS #MDCO #MYOV #NKTR #PCRX #SGMO #ZIOP

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MTSL Issue 862

MTSL Issue 862 (dated 10/12/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ACAD #FPRX #IONS #MDCO #NKTR #SGMO

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MTSL Issue 858

MTSL Issue 858 (dated 8/17/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ACAD #ANTH #BMRN #ESPR #FPRX #INCY #IONS #MDCO #MDGL #NKTR #PCRX #SGMO #XON #ZIOP

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MTSL Issue 856

MTSL Issue 856 (dated 7/13/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #BMRN #IONS #INCY #XON #NKTR #SGMO

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MTSL Issue 854

MTSL Issue 854 (dated 6/15/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ESPR #INCY #XON #NKTR #FPRX #ZIOP

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Ionis

Ionis (IONS) Reports Positive TTR Data, Safety/Patient Death Causes Concern

BioInvest News – IONS – Reports Positive TTR Data, Safety/Patient Death Causes Concern – IONS reported positive Phase III data for inotersen (TTR-Rx) NEURO-TTR results in familial amyloid polyneuropathy (FAP) patients showing a statistically significant benefit in the two co-primary endpoints of modified Neuropathy Impairment Score (mNIS+7, p<0.0001) and the Norfolk Quality of Life Questionnaire-Diabetic Neuropathy (Norfolk QOL-DN, P=0.0006) post 15 months of treatment.

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MTSL Issue 851

MTSL Issue 851 (dated 5/04/17) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ALKS #BMRN #CELG #ESPR #FPRX #INCY #IONS #MDCO #PCRX #SGMO #ZIOP

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Madrigal

‘Access to Management’ Conference Call with Madrigal (MDGL)- 4-4-17

BIOINVEST Access to Management Webinar – Madrigal (MDGL)– We are pleased to announce another BioInvest “Access to Management Call.” Below is the link to the recorded webinar presentation with the Senior Management Team of Madrigal.

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Medicines Company

The Medicines Company (MDCO) Fourier Is Actually More Positive For Inclisiran Than Before

BIOINVEST BREAKING NEWS – The Medicines Company (MDCO) – FOURIER IS ACTUALLY MORE POSITIVE FOR INCLISIRAN THAN BEFORE – Being the first to market is sometimes a double edged sword and is certainly the case with the Amgen’s Repatha (and REGN/SNY’s Praluent). We were at the ACC where the FOURIER* data was presented on Friday.

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Nektar

Nektar (NKTR) – NKTR-181 Successful In Phase III SUMMIT-07 Trial

BIOINVEST BREAKING NEWS – Nektar (NKTR) – NKTR-181 Successful In Phase III SUMMIT-07 Trial & Sets The Stage For A Revolution In Pain Drugs – Raising BUY and TARGET PRICE

The SUMMIT-07 trial met its primary endpoint demonstrating highly significant improved chronic back pain relief with NKTR-181 compared to placebo (p=0.0019). Moreover, the safety and tolerability of ‘181 in SUMMIT supports its breakthrough profile for moderate-to-severe pain relief without the abuse and addiction that has caused the opioid epidemic of today

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Medicines Company

The Medicines Company (MDCO) – Amgen’s FOURIER Outcomes Trial Successful

BIOINVEST Update – The Medicines Company (MDCO) – Amgen’s FOURIER Outcomes Trial Successful – After the close, AMGN announced the long-awaited results of the outcomes trial with Repatha – its PCSK9 monoclonal antibody.

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MTSL Issue 842

MTSL Issue 842 (dated 12/15/16) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ANTH #CBMG #INCY #MDCO

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MTSL Issue 839

MTSL Issue 839 (dated 11/03/16) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ACAD #ALKS #BMRN #INCY #XON #IONS #MDCO #OGXI #SGMO #ZIOP

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MTSL Issue 838

MTSL Issue 838 (dated 10/20/16) of Medical Technology #Stock Letter from BioInvest includes #Biotech Sector Analysis & updates: #ALKS #MDGL #MDCO

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MTSL Issue 835

MTSL Issue 835 (dated 9/8/16) of Medical Technology #Stock Letter from BioInvest includes the #Biotech Sector Analysis & updates from these companies: #ANTH #BMRN #XON #MDCO #SGMO

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MTSL Issue 831

MTSL Issue 831 (dated 7/14/16) of the Medical Technology #Stock Letter from BioInvest includes the #Biotech Sector Analysis as well as updates from the following companies: #ANTH #IONS #MDCO #ZIOP

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MTSL Issue 829

MTSL Issue 829 (dated 6/09/16) of the Medical Technology #Stock Letter from BioInvest includes the #Biotech Sector Analysis as well as updates from the following companies: #ALKS #FPRX #INCY #IONS #XON #NVAX #MDCO #SGMO #ZIOP

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